Press releases

November 21, 2024

ROME Therapeutics Debuts First Preclinical Data of its LINE-1 Reverse Transcriptase (RT) Inhibitors in Neurodegenerative Diseases at 3rd Annual Dark Genome Symposium

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November 7, 2024

ROME Therapeutics to Present Data Supporting LINE-1 Reverse Transcriptase Inhibitors as a Novel Treatment for Autoimmune Diseases at ACR Convergence 2024

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October 8, 2024

ROME Therapeutics, Enara Bio, Nucleome Therapeutics and NYU Langone Health to Host 3rd Annual Dark Genome Symposium

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September 11, 2024

ROME Therapeutics to Participate in 2024 Cantor Global Healthcare Conference

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August 12, 2024

ROME Therapeutics to Participate in 2024 Wedbush PacGrow Healthcare Conference

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March 1, 2024

ROME Therapeutics to Participate in the TD Cowen 44th Annual Health Care Conference

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January 4, 2024

ROME Therapeutics Appoints Heike Keilhack, Ph.D., as Chief Scientific Officer

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December 14, 2023

ROME Publishes Landmark Nature Paper Revealing First High-Resolution Structure of LINE-1 Reverse Transcriptase (RT) for Drug Discovery

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November 16, 2023

ROME Therapeutics Presents First Data to Validate LINE-1 RT as a Novel Target in Autoimmune Diseases and the Therapeutic Potential of its First-in-Class LINE-1 RT Inhibitors

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November 1, 2023

Enara Bio, ROME Therapeutics and Nucleome Therapeutics to Host 2^nd Annual Dark Genome Symposium

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October 4, 2023

ROME Expands Leadership Team with the Appointment of Industry Veteran Kyle Kuvalanka as Chief Financial Officer and Chief Business Officer

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September 12, 2023

ROME Therapeutics Closes Oversubscribed $72 Million Series B Extension to Support Advancement of Lead Program into Clinical Development for Autoimmune Disease

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March 9, 2023

ROME Therapeutics Appoints Keith Wilcoxen, Ph.D., as Executive Vice President, Early Development

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November 10, 2022

ROME Therapeutics Demonstrates Efficacy of its Novel LINE-1 Reverse Transcriptase Inhibitor in Translational Models of Autoimmune Disease

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November 2, 2022

ROME Therapeutics and Enara Bio to Host Inaugural Dark Genome Symposium Convening Industry and Academic Leaders to Catalyze Therapeutic Application of Dark Genome Research

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July 18, 2022

ROME Therapeutics Appoints Industry Veteran Jeff Hatfield as Chair of Board of Directors

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June 30, 2022

ROME Therapeutics Announces Publication of First Crystal Structure of a Human Endogenous Reverse Transcriptase in PNAS

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April 26, 2022

ROME Therapeutics Appoints Nurjana Bachman, Ph.D., as Senior Vice President, Corporate Development and Strategy

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November 8, 2021

ROME Therapeutics Announces Preclinical Data Demonstrating Inhibition of Endogenous Reverse Transcriptase Activity Blocks Immune Response in Autoimmune Disease Models

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September 14, 2021

ROME Therapeutics Secures $77 Million in Series B Financing to Advance Repeatome-derived Pipeline for Cancer and Autoimmune Diseases and Expand Repeatomics Platform

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July 19, 2021

ROME Therapeutics Expands Science Leadership in Oncology, Data Science and New Target Discovery

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March 1, 2021

ROME Therapeutics announces the appointment of Scott Biller, Ph.D. to its board.

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September 28, 2020

ROME Therapeutics announces that it has been named by Fierce Biotech as one of 2020’s Fierce 15 biotechnology companies

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August 19, 2020

ROME Therapeutics Appoints Drug Discovery Veteran Dennis Zaller, Ph.D., as Chief Scientific Officer

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April 27, 2020

ROME Therapeutics Launches to Develop Novel Therapies for Cancer and Autoimmune Diseases by Harnessing the Power of the Repeatome

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News and events

April 17, 2024

Startups probe hidden viruses in the 'dark genome' to treat disease | Nature Biotechnology

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April 2, 2024

Unlocking the Dark Genome for Lupus and Other Autoimmune Diseases | Unseen Upside, a podcast by Cambridge Associates

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March 12, 2024

Dark Genome Hunting with Rosana Kapeller and Marty Taylor | Raising Health™, a podcast by a16z Bio+Health

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November 13, 2023

Enara Bio, ROME Therapeutics and Nucleome Therapeutics Host 2nd Annual Dark Genome Symposium

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October 12, 2023

ROME honored in BostInno 2023 Fire Awards | BostInno

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September 12, 2023

With latest fundraise, Rome Therapeutics works to drug the ‘dark genome’ | BioPharma Dive

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September 12, 2023

Rome Therapeutics advances dark genome drug after completing $72M Series B extension backed by Big Pharma | Endpoints News

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August 4, 2023

"Biotech in Boston" Event Featuring Rosana Kapeller, ROME CEO | Boston Business Journal

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June 14, 2023

Rosana Kapeller Among "Disruptors" Featured on WMIF Panel | World Medical Innovation Forum

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June 8, 2023

Panel: Maximizing Platform Potential, with ROME CSO Dennis Zaller | Longwood Healthcare Leaders Conference

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June 7, 2023

BIO Panel on Oncology Drug Discovery Features ROME CSO Dennis Zaller | BIO International Convention

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May 10, 2023

Panel: Building Strong Relationships with Boards and Investors, featuring Rosana Kapeller | Convergence Forum

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March 1, 2023

Jumping Genes’ Role in Cancer | The Scientist

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November 11, 2022

Podcast: Harnessing the Power of the Repeatome with Dennis Zaller | Biotech2050 podcast

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October 7, 2022

ROME CEO Rosana Kapeller Named to Forbes "50 Over 50" | Forbes

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September 22, 2022

ROME honored in Endpoints 11: The top private biotechs in pursuit of new drugs | Endpoints News

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May 3, 2022

The Mysterious Dark Genome: Panel Featuring Rosana Kapeller, CEO of ROME | World Medical Innovation Forum

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March 8, 2022

The "Dark Genome" with Dr. Rosana Kapeller-Lieberman | GV "Theory and Practice" podcast

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November 21, 2021

ROME Among C&EN’s 2021 10 Start-Ups to Watch | C&EN

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September 14, 2021

Kapeller's ROME bags $77M to strike gold in the backwaters of the genome | Fierce Biotech

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September 28, 2020

ROME Named to Fierce Biotech's 2020 Fierce 15 | Fierce Biotech

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September 10, 2020

Over 160 CEOs Sign MassBio’s Pledge to Create a More Equitable and Inclusive Life Sciences Industry | MassBio

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August 20, 2020

Rome snags Merck, Celgene vet Zaller as new CSO | Fierce Biotech

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August 20, 2020

ROME founder Rosana Kapeller recruits a CSO from the senior ranks of a major league R&D team | Endpoints News

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August 17, 2020

Companies Strain to Outdo Each Other with Work-from-Home Perks (Think Ukuleles) | Wall Street Journal

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August 11, 2020

From Rio to Rome: Rosanna Kapeller on The Long Run | The Timmerman Report

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April 29, 2020

ROME: Tackling repeat DNA for cancer, autoimmunity | BioCentury

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April 28, 2020

At ROME Therapeutics, Kapeller Aims to Turn “Junk” Into New Drugs | Xconomy

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April 27, 2020

The Road to ROME's Series A | GV

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April 27, 2020

ROME Therapeutics launches to probe junk DNA for cancer drug discovery | C&EN

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April 27, 2020

ROME Therapeutics debuts with $50M and Rosana Kapeller at the helm | Fierce Biotech

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April 27, 2020

GV joins $50 million round in ROME Therapeutics to research ‘junk DNA’ for cancer therapies | VentureBeat

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April 27, 2020

Nimbus founder Rosana Kapeller has a new company, with $50M and an eye on the ‘repeatome’ | Endpoints News

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Scientific presentations

November 15, 2023

Elevated LINE-1 Expression in SLE Keratinocytes Leads to LINE-1 Reverse Transcriptase-dependent Type I Interferon Responses | ACR Convergence 2023

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November 9, 2023

Mechanism-guided quantification of LINE-1 reveals p53 regulation of both retrotransposition and transcription | EMBO Workshop: The Mobile Genome

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May 12, 2023

Mechanism-guided quantification of LINE-1 reveals p53 regulation of both retrotransposition and transcription | bioRxiv

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January 11, 2023

ROME Therapeutics company presentation | 41st J.P. Morgan Healthcare Conference

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November 14, 2022

LINE1 Reverse Transcriptase Inhibitors Abrogate Type 1 Interferon Responses | American College of Rheumatology Convergence 2022

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June 30, 2022

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific inhibition | PNAS

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June 5-9, 2022

Sensitive Detection of LINE-1 Retrotransposition Across Cancer Uncovers Biological Correlates | The Mobile DNA Conference: Evolution, Diversity, and Impact

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June 5-7, 2022

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) displays a lamivudine resistant genotype and phenotype | 4th Symposium of the Canadian Society for Virology

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April 20-23, 2022

Human endogenous retrovirus-k (HERV-K) reverse transcriptase (RT) forms an asymmetric homodimer reminiscent of HIV-1 RT | Cold Spring Harbor Laboratory: Fifty Years of Reverse Transcriptase

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March 23, 2022

Reverse transcriptase inhibition disrupts repeat element life cycle in colorectal cancer | Cancer Discovery

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