Welcome to the repeatome

A new frontier in biology
A new way to conquer disease

Vast stretches of human DNA have long been dismissed as junk. Most of this “dark genome” is comprised of repetitive sequences, collectively known as the repeatome. We have now discovered that these repeats can play a critical role in human health, such as by switching on the innate immune response under stress.

Unlocking the repeatome will enable us to discover powerful new classes of medicines for cancer and autoimmune diseases.

That is our mission at ROME.

Latest news and presentations

May 12, 2023

Mechanism-guided quantification of LINE-1 reveals p53 regulation of both retrotransposition and transcription  |  bioRxiv

March 9, 2023

ROME Therapeutics Appoints Keith Wilcoxen, Ph.D., as Executive Vice President, Early Development

January 11, 2023

ROME Therapeutics company presentation | 41st J.P. Morgan Healthcare Conference