Welcome to the repeatome

A new frontier in biology
A new way to conquer disease

Vast stretches of human DNA have long been dismissed as junk. Most of this “dark genome” is comprised of repetitive sequences, collectively known as the repeatome. We have now discovered that these repeats can play a critical role in human health, such as by switching on the innate immune response under stress.

Unlocking the repeatome will enable us to discover powerful new classes of medicines for cancer and autoimmune diseases.

That is our mission at ROME.

Latest news and presentations

November 11, 2022

New frontier in biology: harnessing the power of the repeatome with Dennis Zaller  |  Biotech2050 podcast

November 14, 2022

LINE1 Reverse Transcriptase Inhibitors Abrogate Type 1 Interferon Responses | American College of Rheumatology Convergence 2022

November 10, 2022

ROME Therapeutics Demonstrates Efficacy of its Novel LINE-1 Reverse Transcriptase Inhibitor in Translational Models of Autoimmune Disease